Pangenome Aquaculture Consortium

The Pangenome Aquaculture Consortium (PAC) is an international research initiative uniting scientists from Chile, China, Brazil, and Uruguay to build high-quality pangenome reference assemblies for the world's most important aquaculture species. Unlike traditional single-reference genomes, pangenomes capture the full genomic diversity of a species across populations — revealing structural variants, novel genes, and haplotype variation invisible to conventional approaches.

PAC resources are designed to accelerate genomic selection, trait mapping, and sustainable breeding programs worldwide. The PAC Data Portal is the open-access repository for all data generated by the consortium, providing a centralised, curated, and freely accessible resource for the global research community.

Collaborators

Publications

1. Yáñez JM, Xu P, Carvalheiro R, Hayes B. Genomics applied to livestock and aquaculture breeding. Evol Appl. 2022 Apr 18;15(4):517–522. doi: 10.1111/eva.13378
2. Shi Y, Chen B, Kong S, Zeng Q, Li L, Liu B, Pu F, Xu P. Comparative genomics analysis and genome assembly integration with the recombination landscape contribute to Takifugu bimaculatus assembly refinement. Gene. 2023 Jan 15;849:146910. doi: 10.1016/j.gene.2022.146910
3. Chen B, Bai Y, Wang J, et al. Population structure and genome-wide evolutionary signatures reveal putative climate-driven habitat change and local adaptation in the large yellow croaker. Mar Life Sci Technol. 2023. doi: 10.1007/s42995-023-00165-2
4. Li B-J, Chen L, Yan M-Z, et al. Intercross population study reveals that co-mutation of mitfa genes in two subgenomes induces red skin color in common carp (Cyprinus carpio wuyuanensis). Zoological Research. 2023;44(2):276–286. doi: 10.24272/j.issn.2095-8137.2022.388
5. Wang M, Chen L, Zhou Z, et al. Comparative transcriptome analysis of early sexual differentiation in the male and female gonads of common carp (Cyprinus carpio). Aquaculture. 2023;563(Part 1):738984. doi: 10.1016/j.aquaculture.2022.738984
6. Yáñez JM, Barra A, López ME, Moen T, Garcia BF, Yoshida GM, Xu P. Genome-wide association and genomic selection in aquaculture. Reviews in Aquaculture. 2023;15:645–675. doi: 10.1111/raq.12750

API Access

All data is accessible programmatically via the REST API. An interactive Swagger UI and an OpenAPI 3 schema are available for machine-readable documentation.